Annova Plus
Annova Plus consists of an immediate release Esomeprazole Magnesium layer & an enteric coated Naproxen core. Esomeprazole is released first into the stomach, prior to the dissolution of Naproxen in the small intestine.
Naproxen is a NSAID that inhibits inflammatory reactions and pain by decreasing activity of cyclo-oxygenase, which is responsible for prostaglandin synthesis; has antipyretic and analgesic effects. Esomeprazole is an S-isomer of omeprazole which is a proton pump inhibitor, inhibits gastric acid secretion by inhibiting H+/K+-ATPase enzyme system at secretory surface of gastric parietal cells.
Features
| Product Name | Annova Plus |
| Generic Name | Naproxen & Esomeprazole |
| Formulation | Annova Plus 375/20 Tablet: Each tablet contains Delayed Release Naproxen USP 375 mg & Immediate Release Esomeprazole Magnesium Trihydrate USP equivalent to Esomeprazole 20 mg. Annova Plus 500/20 Tablet: Each tablet contains Delayed Release Naproxen USP 500 mg & Immediate Release Esomeprazole Magnesium Trihydrate USP equivalent to Esomeprazole 20 mg. |
| Available Pack Size | Annova Plus 375/20: 7×6’s Annova Plus 500/20: 4×6’s |
| Available Strength | Naproxen & Esomeprazole 375/20 & 500/20 mg tablet. |