Roflast

Roflumilast is a selective and long acting PDE4 inhibitor, a non-steroid, anti-inflammatory agent designed to target both the systemic and pulmonary inflammation associated with COPD. The mechanism of action is the inhibition of PDE4, a major cyclic adenosine monophosphate (cAMP) - metabolizing enzyme found in structural and inflammatory cells important to the pathogenesis of COPD. This mechanism of action and the selectivity also apply to roflumilast N-oxide, which is the major active metabolite of Roflumilast.

Features